TP53 DRIVES ABSCOPAL EFFECT BY SECRETION OF SENESCENCE-ASSOCIATED MOLECULAR SIGNALS IN NON-SMALL CELL LUNG CANCER

TP53 drives abscopal effect by secretion of senescence-associated molecular signals in non-small cell lung cancer

Abstract Background Recent developments in abscopal effect strongly support the use of radiotherapy for the treatment of metastatic disease.However, deeper understanding of the molecular mechanisms underlying the abscopal effect are required to best benefit a larger proportion of patients with metastasis.Several groups including ours, reported the

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Cor triatriatum with mitral stenosis: A diagnostic dilemma

Cor triatriatum sinister is an extremely rare congenital heart defect.Very few cases have been reported for cor triatriatum associated 9x11 pergola with mitral regurgitation.We are reporting an exceptional case of cor triatriatum associated with calcified mitral valve resulting mitral stenosis.Preoperatively, mitral stenosis was underestimated due

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The Economic Value of Endangered Languages

In a world where more than half of the 6,500 languages are under the threat of extinction, this paper challenges the conventional view that language preservation lacks concrete economic benefits.Investigating the intricate relationships between monolingualism, cultural identity, and economic dynamics, it illuminates the diverse values that language

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